A new large-scale study has raised concerns about a widely used class of medications often taken for back pain, arthritis, and other chronic pain conditions: anticholinergic drugs. Researchers found that long-term use of these medications—particularly at higher doses—was associated with a significantly increased risk of developing dementia, including Alzheimer’s disease.

While the study shows an association (not proof of causation), the findings are strong enough that experts are urging both patients and doctors to reevaluate long-term use, especially in older adults.

🔍 What Are Anticholinergic Drugs?
Anticholinergics block a key brain chemical called acetylcholine, which is essential for memory, learning, and muscle function. While this effect can help with conditions like overactive bladder, allergies, or muscle spasms, it also dampens cognitive activity—especially with prolonged use.

Common anticholinergic medications include: